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In vitro, Gq protein and b-arrestin1 are not necessary for fluoxetines effects on A1 astrocyte activation, and downstream signaling through astrocytic 5-HT 2B R is responsible for fluoxetines inhibitory effects on A1 astrocyte activation in primary culture

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Cho CS et al

The Role of Neurosteroids in Memory Deficits Associated With Schizophrenia The cognitive deficits associated with schizophrenia are caused by multiple factors, and elucidating a single causative part of the cognitive component would provide some hope for understanding memory and a basis for therapeutic discovery

Moreover, there are credible evidences that GEN produced hepatoprotection through modulating the expression and phosphorylation of epidermal growth factor receptor (EGFR) in experimental fibrosis (Rodriguez and Alvarez, 2016)

Cui Q, Wang JQ, Assaraf YG, Ren L, Gupta P, Wei L, et al