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Rowland DL, Tai W

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Prebiotics provide the necessary nutrients for beneficial bacteria to thrive, while probiotics introduce live beneficial bacteria into the gut

Participant Selection We recruited participants aged 18 to 55 years, meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition ( DSM-IV ) criteria for bipolar disorder (type I or II), currently depressed, scoring greater than or equal to 20 on the MADRS at screening and baseline