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It also helps to reduce the shrinkage of your skin and make your skin free from wrinkles and fine lines which have been caused due to premature aging and other oxidative stresses

Eur J Biochem 267: 49044911, 2000

When used in combination with levodopa, COMT inhibitors have been shown to reduce the amount of off time experienced by patients with advanced Parkinson's disease, as well as increase the amount of on time and reduce the required dose of levodopa

While there are risks associated with epidural injections, they rarely occur