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Zebrafish genes 87% homology with human genes, and their biological structures and physiological functions are highly similar to those of mammals 18

doi: 10.1186/s41232-024-00342-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 3.Kaur J, Farr JN

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Cytoskeletal Crosstalk in Cell Migration

Moreover, the SU11274 significantly reduced the in vitro migratory capacity of myeloma cells and treatment by the SU11274 decreased primary tumor growth and the capacity for liver colony formation in SCID mice [68]

Regardless, the reproduction of L -2HG in the cytosolic compartment is difficult to eliminate, and its persistence can lead to the aggressive reprogramming of metabolism to fuel uncontrolled cancer cell proliferation