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The results are known to include: Lower levels of stress hormone Reduced fear responses Greater emotional calm Improves the adaptability to change 8

doi: 10.1016/j.cmet.2014.01.018 66 GrahamTEYangQBlherMHammarstedtACiaraldiTPHenryRRet al

CPT Pharmacom Syst Pharmacol

Where semaglutide, a GLP-1-only agonist, produces roughly 15% body weight loss on average, tirzepatide pushes past 20%

it is not, on its own, evidence sufficient to support a claim of life extension in humans absent independent randomized trials

& Nattel, S
