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The prognostic value of IDH mutations and MGMT promoter status in secondary high-grade gliomas

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doi: 10.1210/me.2015-1232 51 JaisABrningJC

The trials targeted gastrointestinal dysmotility and ileus

The RD adopts the evolutionarily conserved Bateman module, consisting of two tandem CBS motifs (CBS-1 and CBS-2) and a surface-exposed loop (residues 516525) extending from a CBS-2 motif (Supplementary Fig

These findings are consistent with those for other antioxidant enzymes: for example, lack of peroxiredoxin 3, a mitochondrially localized antioxidant enzyme, also augments apoptotic signaling in some cell types (60)