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EXAMPLE 5: EFFECT OF HYDROXYPROPYL-B-CYCLODEXTRIN CONCENTRATION ON SEMAGLUTIDE CHEMICAL STABILITY This example shows the concentration-dependent effect of HP-B-CD on the chemical stability of semaglutide

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Such changes in gut microbial diversity can compromise the integrity of the epithelial barrier, leading to leaky gut or dysbiosis, in which increased intestinal permeability permits the passage of bacteria, toxins, and metabolites, thereby causing immune activation and intestinal disorders in the fetus [17]