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Chorea associated with antiphospholipid antibodies in a patient with Kabuki syndrome

Similar content being viewed by others Introduction The presence of the blood-brain barrier (BBB), a tightly interconnected network of blood vessels and endothelial cells that restricts the entry of foreign particles larger than 100 nm into the brain, poses considerable challenges and complexities in advancing therapeutic strategies for neurodegenerative diseases (NDs) 1

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Understanding the interactions at the molecular level will also be beneficial for designing more effective therapeutic strategies that not only target intracellular regeneration but also optimize the surrounding microenvironment to enhance neural recovery

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