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The proposed mechanisms: Ketone bodies (-hydroxybutyrate) have direct anti-inflammatory effects on macrophages Complete elimination of immune-triggering food antigens Fiber elimination alters colonic microbiota, reducing fermentation-driven inflammation The honest limitations: 10 patients, retrospectively selected

Colodete DAE, Grace AA, Guimaraes FS, Gomes FV

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Here, we propose a high-throughput screening (HTS) framework that integrates machine learning (ML) models with density functional theory (DFT) calculations to accelerate the prediction and validation of infrared-detection materials [see Graphical Abstract]

Pairing Kisspeptin-10 with a reduced-dose SERM creates complementary mechanisms: kisspeptin stimulates GnRH release from above while the SERM blocks estrogen negative feedback from below

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