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[ 78 , 242 ] BACH1 fosters the growth and spread of hepatocellular carcinoma (HCC) by upregulating genes related to cell motility, like protein tyrosine kinase 2 (PTK2) and insulinlike growth factor 1 receptor (IGF1R)

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It activates the Akt survival pathway, recruits stem cells to injury sites, promotes endothelial cell differentiation for angiogenesis, and upregulates matrix metalloproteinases for tissue remodeling

Autophagy was enhanced in MPP+-treated SH-SY5Y cells upon treatment with coated nanoparticles, as confirmed by monodansylcadaverine (MDC) staining