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Generally acting as a tumor suppressor, ChaC2 decreases GSH levels in tumor cells, instigates mitochondrial apoptosis and autophagy via UPR and hinders tumor cell proliferation and migration in vitro and in vivo (79)

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In preclinical research it is linked to protection of the gastrointestinal lining, support of angiogenesis, and signaling involved in tendon and ligament healing