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Are histological changes that persist after the protocol ends, provided the injury or stressor that caused the original damage is no longer present

Why is the HMP important

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NQO1 has been shown to stabilize the degradation of ODC by binding to it and protecting it from 20S proteasomal degradation

Elife 3 , e02439 (2014)

Some dermatologists may also recommend a triple combination cream containing hydroquinone 4%, tretinoin 0.05%, and flucinolone acetonide 0.01% in combination with oral tranexamic acid to treat melasma and lighten hyperpigmentation
