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"Cats have a genetic deficiency that makes cats vulnerable to acetaminophen toxicity." Cats have a genetic deficiency in a metabolic pathway in the liver that breaks down medications, called the 'glucuronide conjugation pathway'

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Alcoholism, malabsorption, prolonged stress, tapeworm infestation, vegan diets, celiac, hyperthyroidism, hepatic-biliary tract disease, persistent diarrhea, ileal resection, pancreatic cancer, renal disease, macrobiotic diets or other restrictive diets

[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Uebel-von Sandersleben H., Rothenberger A., Albrecht B., Rothenberger L.G., Klement S., Bock N

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For example, METTL3 promotes ferroptosis through m6A methylation of HMGB1, leading to cartilage degradation and pain in OA