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Who benefits most from CLA and L-carnitine People with low baseline L-carnitine due to dietary restriction, older age, or certain metabolic limitations sometimes show clearer responses to L-carnitine

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Presynaptic cytoplasmic Ca 2+ can be depleted by several complementary mechanisms, including sarcoendoplasmic reticulum Ca 2+ -ATPase (SERCA) to the endoplasmic reticulum (ER), plasma membrane Ca 2+ -ATPase to the extracellular space, and MCU to the mitochondrial matrix [51,52,53]