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We compared how treatments that increase only the expression of GCLC versus those that increase the expression of both GCLC and GS affect the capacity to synthesize GSH
doi: 10.1152/japplphysiol.00431.2011

10.3410/B4-14 F1000 Biol

IFN- levels in the TME also downregulate SLC7A11, a key protein involved in the system x c complex
Repeated-dose oral N-Acetylcysteine in Parkinsons disease: Pharmacokinetics and effect on brain glutathione and oxidative stress
The authors pointed specifically to the growth hormone receptor upregulation as one of the main mechanisms