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ER function is impaired by the continuous degradation of ER fragments, eventually leading to cell death

As diabetic nephropathy rats received streptozotocin (60 mg/kg, i.p), daily treatment with two dose levels of ethanolic extract of leaf Artemisia vulgaris (EEAV) showed a significant dose-dependent decrease in various renal function parameters like urinary albumin excretion rate (UAER), type IV collagen excretion, total proteins in urine, creatinine, advanced glycation end products, excretion of glycosaminoglycans and a significant increase in urinary creatinine, glycosaminoglycans, urine volume

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During the mixing process, gluten strands interlace and reconfigure, forming a network that traps the CO2 gases generated during fermentation

Int J Biol Macromol 194:676687