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Indeed, lipid peroxidation damage, which is consistent with ferroptotic injury, is a prominent feature of degenerating motor neurons in individuals with ALS [236]
Intracellular pathways such as ERK and IRS2-AKT are highly regulated by stress and drugs of abuse and involved in regulation of mood-related disorders and drug-induced neuroplasticity 73,74
Engel, P., Gomez-Puerta, J
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