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In addition to its participation in the WWC, ascorbate is also required for the regeneration of lipid-soluble antioxidants, particularly tocopherols and tocotrienols (vitamin E), which protect the polyunsaturated fatty acids in the thylakoid membranes from oxidation to chromanoxyl radicals by singlet oxygen

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In this report we demonstrate the efficacy of multiplexing the CellTox Green Cytotoxicity Assay with the GSH/GSSG-Glo Assay to determine both the cytotoxic and oxidative effects of compounds on cultured cells in a single assay plate

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La niacine est un cofacteur ncessaire dans le cycle anabolique de la mthionine, soutenant des enzymes comme la dihydrofolate rductase

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This lack of regulation is a significant concern

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N Engl J Med 2013;368:149-60

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