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Intestinal probiotics may exert protective effects against ferroptosis by chelating metal ions, scavenging or reducing ROS, and modulating key ferroptosis-related enzymes (43, 44)

The role of Akkermansia muciniphila in obesity, diabetes and atherosclerosis

However, they activate receptors through similar mechanisms [12]

As a food supplement rather than a licensed medicine, berberine products are not subject to the same quality controls as prescription medications, meaning contamination, mislabelling, or inconsistent dosing may occur

Evidence Snapshot The STEP trials demonstrated significant weight reduction with semaglutide, with gastrointestinal side effects most prominent during dose escalation. Long-term micronutrient outcomes were not primary endpoints