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Dec;2020 Br J Sports Med

Oxidative stress and endothelial dysfunction in hypertension

doi: 10.1038/s41467-020-15136-9

More keratinocyte wound healing and migration was shown in the experimental group (1.22 g/mL)

Although many of the genes up- and downregulated by GSTP1 deletion are associated with the RAS/MAPK pathway (Supplementary Table 1), we did not detect a significant difference in RAS/MAPK pathway activation, using a quantitative RAF-1- binding/Ras GTPase ELISA to assess pathway activation in GSTP1 knockdown cells (data not shown)

While redox homeostasis via enhanced glutathione production is commonly associated with the normal physiological role of NRF2, collectively our results suggest that NRF2-dependent cancer cell growth does not require this enhanced glutathione production