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Various studies show that viruses are responsible for chronic fatigue syndrome, as it follows the form of acute infections, although not in the affirmative

This biological capability provides a plausible explanation for why some patients experience a relapse of symptoms weeks or months after completing their initial antibiotic therapy, fueling the ongoing debate about the need for novel, targeted antimicrobial treatments

Cognitive deficits Cognitive dysfunction in SSD impacts multiple cognitive domains, often precedes psychosis onset [114] and is closely associated with poorer social and occupational functioning [115]

Verneau, J., Sauts-Fridman, C

For example, amyloid- accumulation in the pontine tegmental area and ventral medulla is found to follow a course similar to that of the reduction of REM sleep in APP-NLGF mice (Maezono et al., 2020), while reduced numbers of pedunculopontine tegmentum ChAT-positive neurons correlate with reduced REM sleep in Tg2576 mice (Zhang et al., 2005)

70 The amino acid change at position 495 impairs SOCS2 binding and leads to a reduced downregulation of the receptor