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These tumours may involve the optic nerve, chiasm and/or hypothalamus

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After the treatments, biosafety is systematically evaluated

, 15 , 1-12, Food and Nutrition Board, Institute of Medicine (2000) Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids: A Report of the Panel on Dietary Antioxidants and Related Compounds, Subcommitties on Upper Reference Levels of Nutrients and of Interpretation and Use of Dietary Reference Intakes, and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes , National Academy Press, Washington, 529 p

ROS, by binding to NO, can contribute to the formation of the highly reactive radical peroxynitrite (ONOO ), which impairs the proper function of eNOS [78]