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Alterations on the morphology, nitric oxide synthesis and activity of platelets reproduced in rats as possible biomarkers for depression are reversed by fluoxetine
(193) Toumpanakis, A

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These changes likely influence the development of physical frailty, cognitive decline as well as negative cardiovascular events

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Soluble Vpr released from infected microglia induces oxidative stress, disrupts cellular signaling, and impairs neuronal glutamate transmission [135, 137]
