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The volume required to cause harm via subcutaneous injection would exceed 200mL injected directly into a vein

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[DOI] [PubMed] [Google Scholar] Blum R., Meyer K.C., Wnschmann J., Lendzian K.J., Grill E

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Treatment depends on the cause and may include pain relievers, antibiotics, antihistamines, or fever reducers

Glial cells have also been shown to release glutamate and modulate synaptic transmission and plasticity (see Perea et al., 2009 for review)
