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Interestingly, the lack of mitochondrial GSH (mtGSH) in Gclc fl/fl Mb1-Cre + FoB (Supplementary Fig

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doi: 10.1186/s12913-022-07644-9 [DOI] [PMC free article] [PubMed] [Google Scholar] 9.Donnez J, Dolmans MM

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for example, it protects membranes by maintaining the reduced state of both -tocopherol and zeaxanthin, it prevents the oxidative denaturation of proteins under stress conditions by protecting their thiol groups, and it serves as a substrate for both glutathione peroxidase and glutathione S -transferase