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Vitamin B12 deficiency causes fatigue and other ME/CFS-like symptoms so it should be excluded before a diagnosis of ME/CFS is made, especially in people where there is no clear infective onset

For those with subclinical lows

Determine Concentration (example: 10 mg vial 1 mL water = 10 mg/mL): Calculate Dosage Volume (example: 1 mg dose 10 mg/mL = 0.1 mL): Convert to Syringe Units: Using a standard U-100 (1 mL/100 unit) insulin syringe, 0.1 mL equals 10 units

References Heffernan, M., Summers, R.J., Thorburn, A., Ogru, E., Gianello, R., Jiang, W.J., & Ng, F.M

They can diagnose and treat the issue

It means they should approach those goals carefully, with proper medical screening, realistic expectations, and professional guidance