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Keywords: synuclein, blood transfusion, gutbrain axis, protein aggregation, Parkinson's disease This graphical abstract summarizes the major components of this review on Parkinson's disease, including epidemiological trends, risk factor classification, peripheral and molecular pathogenesis, and both preventive and therapeutic strategies

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Conversely, zinc supplementation has been shown to reverse these inhibitory effects

It suppresses TNF-alpha and IL-6, two inflammatory markers consistently elevated in alcohol-related organ damage (Koyuncu et al., 2025)

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43 DavalosD.GrutzendlerJ.YangG.KimJ.ZuoY.JungS.et al (2005)
