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Indeed, loss of function due to mislocalization of TDP-43 causes aberrant cryptic splicing in genes including STMN2 and UNC13A that drive the progression of ALS[1215, 17]

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JMAJ 47(8):365 Araki T, Holick MF, Afonso BD, Charlap E, Romero CM, Rizk D (2011) Viamin D intoxication with severe hypercalcemia due to manufacturing and labeling errors of two dietary supplements made in the United States