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However, in addition to promoting the activation of CD8 + T cells, the metabolites of ferroptotic cancer cells also have negative effects on the regulation of CD8 + T cells to a certain extent

In cancer, there is an increase in metabolism along this pathway

The points below give a quick map of what the rest of the article explains in more depth

Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms

The mitochondrion is the compartment considered to be the major source of ROS production in the cell and, therefore, this organelle is highly susceptible to suffer oxidative damage

It provides neuroprotection and cellular antioxidant defence, suggesting its potential pharmaceutical use for the treatment of neurodegenerative disorders