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doi:10.1016/j.burns.2014.06.001

For a 42 mg vial, draw 2.0 mL

Ulcers and inflammation result in many symptoms of Crohns, but the cause of bloody diarrhea with UC is due to the inflammation in the colon, causing frequent trips to the loo

Following, the complex enters the nucleus, where it binds to another transcriptional factor and to the DNA producing induction and gene rebuke, what finally leads to its anti-inflammatory, immunosuppressant and mineral corticoid effect

(14) (14) Preparation Fmoc-Glu(otBu)-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin Fmoc-Glu(otBu)-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin (13)Fmoc-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin(20DMF)5203DMF3DMF2Fmoc-Glu(otBu)-OH1.1gDIEA0.4mlTBTU0.56gHOBT0.2gDMF10ml1.53DMF3DMF2Fmoc-Glu(otBu)- Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin In the Fmoc-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin of step (13), add decapping reagent ( 20% piperidine in DMF), reacted at room temperature for 5 minutes, drained, re-added capping agent and reacted at room temperature for 20 minutes, washed 3 times with isopropanol, washed 3 times with DMF, washed 2 times with distilled DMF, drained , add Fmoc-Glu(otBu)-OH1.1g, DIEA0.4ml, TBTU0.56g, HOBT0.2g, DMF10ml, react at room temperature for 1.5 hours, dry with a vacuum pump, wash with isopropanol for 3 times, DMF for 3 times, repeat The steamed DMF was washed twice and dried to obtain Fmoc-Glu(otBu)-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly- Leu-Val-Wang Resin