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Hannon AM, Thompson CJ, Sherlock M

Disc problems may benefit from improved angiogenesis and collagen synthesis

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Among these, PTEN loss is particularly consequential, as it leads to dysregulation of the PI3K/AKT pathway, promoting unchecked cell growth and therapy resistance

10.1126/science.102.2651.400 87 PawliukR.WestermanK

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