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10.1155/2011/796025 9 KlicekR.KolencD.SuranJ.DrmicD.BrcicL.AralicaG.et al (2013)

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NNMT in Aging and Metabolic Disease 7.1 Obesity, Insulin Resistance, NAFLD/NASH High NNMT expression in adipose tissue correlates with obesity , insulin resistance , and progression of nonalcoholic fatty liver disease to NASH , due to decreased NAD and global methyl depletion

[36] [37] In likely relation to this fact, endogenous oxytocin concentrations in the brain have been found to be as much as 1000-fold higher than peripheral levels

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