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Our identification of VRK2-mediated SLC7A11 trafficking suggests a potential immune evasion mechanism, as SLC7A11-high tumors often display T cell exclusion phenotypes [37], warranting future investigation into whether VRK2 expression could predict therapeutic response to combined ferroptosis inducers and immune checkpoint inhibitors

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doi: 10.1136/jnnp-2019-321913

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[DOI] [PMC free article] [PubMed] [Google Scholar] 259.Liang T.J

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