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If the GP says that she doesn't have macrocytic anaemia so doesn't need this pattern of treatment, you could point out that NICE guidelines for B12 deficiency say that "Note: clinical features of vitamin B12 deficiency can occur without anaemia and without low serum levels of vitamin B12." cks.nice.org.uk/topics/anae

For example, some B12 comes in powder form youll need to add water before injecting

[DOI] [PMC free article] [PubMed] [Google Scholar] 227.Ogura Y, Kitada M, Xu J, Monno I & Koya D CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD/NADH ratio and Sirt3 activity in renal tubular cells in diabetic rats