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Siglecs evolved under different sialic acid environments and often show preferences: some Siglecs bind Neu5Gc better, others prefer Neu5Ac

This was consistent with the reported cDDP half maximal inhibitory concentrations IC 50 (48 h) of 1.0 M and 32.4 M for S and R cells, respectively [30]

Based on a large database ( n = 493 experiments) from six laboratories a GEF of 126 mutant colonies per 10 6 cells (mean MFcorr = 99 10 6 colonies

Acetaldehyde then enters the mitochondria where it is oxidized to acetate by mitochondrial aldehyde dehydrogenase (ALDH)

In ovarian cancer, the levels of Gln, glutamate, and GSH in the cisplatin-resistant cell line A2780cis were significantly higher than those in the A2780 cells, while the expression of GS decreased

de Ostrovich, K