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Historically, due to the lack of safety data, melatonin supplementation was not recommended for women who are pregnant or nursing

10.1039/d1fo02659c [DOI] [PubMed] [Google Scholar] Chinetti G., Fruchart J.-C., Staels B

Specifically, the classic arm of the hepatic RAS, which comprises AngII and AT1R, is pathologically over-activated

[DOI] [PMC free article] [PubMed] [Google Scholar] 434.Hensley K., Benaksas E.J., Bolli R., Comp P., Grammas P., Hamdheydari L., Mou S., Pye Q.N., Stoddard M.F., Wallis G., et al

What this means for you: if your GGT is markedly elevated, especially together with a raised AST, that combination is a more informative warning sign than looking at ALT alone

Post-synaptic neuron firing