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Due to declining soil quality from intensive over-farming making the soil deficient in cobalt, and because our vegetables are super-washed (because we would rather not eat soil/manure) vegans don't get enough B12 without supplementation and fortification

People with digestive issues may struggle to absorb oral supplements at all

This makes AOD-9604 relevant to research involving metabolic signaling, adipose tissue biology, body-composition pathway models, and cellular energy utilization under controlled experimental conditions

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This is crucial for anyone with conditions that impair nutrient absorption from food or pills