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Iron chelators such as deferoxamine mesylate and ferroptosis inhibitor ferrostatin-1 have been found to significantly alleviate the cell toxicity induced by aristolochic acid I

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Harris BE, Song R, Soong SJ, Diasio RB (1990) Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion

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By constructing and analyzing networks of genes, we can elucidate the regulatory circuits that drive cancer progression

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In short, they are responsible for supporting energy production, detoxification, antioxidant defenses, the nervous system, and so much more

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J Clin Invest 120(3):694705 Ahn JB et al (2010) Circulating endothelial progenitor cells (EPC) for tumor vasculogenesis in gastric cancer patients

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10.1007/s11101-008-9109-1 48 KuranD.PogorzelskaA.WiktorskaK

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