homocysteine and glutathione peroxidase-1 Dysregulated metabolism cardiovascular disease and clinical treatments | Molecular and Cellular Biochemistry Frontiers | Mechanism of homocysteine-mediated

Methylmalonyl-CoA epimerase is encoded by the MCEE gene

Proc Natl Acad Sci USA 99:12591263 Pastore A, Federici G, Bertini E, Piemonte F (2003) Analysis of glutathione: implication in redox and detoxification

It is an excellent radiotracer for imaging both MM and CD38-positive lymphoma, outperforming [ 18 F]FDG PET/CT in MM imaging

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In other words, when the up-regulation of system Xc reaches a certain threshold, Glu toxicity and ferroptosis will be aggravated