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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Aging Mice

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For instance, inhibiting SASP may reduce inflammation but could also impair the immune systems ability to fight infections or prevent cancerous growths.194 Similarly, inhibition of mTOR can impair immune function, and restoring NAD + levels could potentially affect metabolic processes.198 As such, careful monitoring of patients undergoing senomorphic therapy is necessary to prevent adverse effects

TOR signaling in growth and metabolism

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