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doi:10.1056/NEJM200005183422018

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PMID 10715364

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and Aortal Hypotension

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An increase in phosphorylation of adenosine monophosphateactivated protein kinase (AMPK) was seen in the hearts of the rats treated with both leptin and MTII (indicative of an increase in AMPK activity)

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Labial or oral hyperpigmentation may be accompanied by nail pigmentation

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