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C.NagaiR.UchidaK.et al

Emerging evidence indicates that lactate serves as an immunomodulator [288] and mediates differentially expressed gene production [289], revealing that lactate may be the white swan of reshaping energy metabolism rather than a glycolytic waste product. Metabolites derived from nonimmune cells have been confirmed to affect the glycolysisOXPHOS axis of immune cells and then reshape their phenotype [290]

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Negative schizophrenic symptoms and more severe psychiatric symptoms seem to correlate with higher D3 levels (Kwak et al., 2001

Skin aging (reduced collagen, wrinkles): Fibroblasts lose repair capacity, leading to extracellular matrix degradation