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Experimental studies employing cell lines revealed that PINK1 deficit leads to swelling, shortening (Dagda et al
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doi: 10.1111/aor.13096 154 KronPSchlegelAMullerXGaspertAClavienP-ADutkowskiP
Although minocycline showed anti-inflammatory and neuroprotective effects preclinically and crosses the bloodbrain barrier [195, 196], randomized clinical trials in HAND did not improve cognitive benefit [197]
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