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Allicin inhibits oxidative stress-induced mitochondrial dysfunction and apoptosis by promoting PI3K/AKT and CREB/ERK signaling in osteoblast cells

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GR also manifests a protective feature against OxS, and its overexpression in heart tissue of a Klotho-hypomorphic (antiaging gene) deficient male mice resulted in heart failure and apoptotic prevention [81]
The study found that the exosomal SP94-Lamp2bRRM, which targets HCC, aids in delivering small interfering RNA to improve sorafenib-induced ferroptosis by inhibiting the expression of GPX4 and DHODH

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Lung Cancer In a study with squamous cell carcinoma and bronchioalveolar carcinoma of lung malignancies, CD44v5 and CD44v6 have been shown to promote tumor metastasis [29, 50]
