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In the context of host physiology, the commensal microbiome has a vital role in numerous processes including fiber breakdown, vitamin production, e.g., biotin, folate, and vitamin K, xenobiotic metabolism, and immune system function and maturation [137]

Treatment volumes The definition of treatment volumes is critical to ensure adequate tumor coverage and minimize exposure to healthy tissues

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Correlating longitudinal multi-omics data from large, well-annotated patient cohorts with clinical outcomes will thus enable accurate patient stratification, guide therapeutic decision-making, and increase the success rate of clinical trials