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Results: We found marked neuronal alterations in the cortex and hippocampus of LPS intoxicated animals associated with higher inflammatory cytokines expression cyclooxygenase (COX2), tumor necrotic factor-alpha (TNF-)
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However, when ROS production surpasses the capacity of antioxidant defenses, oxidative stress ensues, leading to deleterious interactions with cellular components
[PubMed 9675768] 2306
Lipid-OH = lipid hydroxide
Psychiatry 56 , 638643 (1993)
