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Guarana and caffeine provide a dual-action energy boost, enhancing alertness and physical performance, while L-carnitine aids in the transport of fatty acids into the mitochondria for energy production

Disclosure The authors declare that they have no competing interests

Limited treatment efficacy and low response rates with this combination led to the early termination of the study

Late normalization of melanocytomalytic intraocular pressure elevation following excision of iris melanocytoma

Research uses MT-1 to establish the reference pharmacodynamic profile for MC1R activation , characterising concentration-response relationships, receptor internalisation kinetics, and downstream melanin synthesis biology that serve as the benchmark for evaluating other melanocortin agonists and antagonists at MC1R

Black stools can be a medical warning sign, particularly when caused by gastrointestinal bleeding