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122 showed the difference between the pharmacokinetic profile in preterm babies and adults caused by immature liver and poor renal excretion and concluded that a 2-h infusion of 0.1 g/kg/h increased plasma melatonin from undetectable to approximately peak adult concentration
Which is the theory that cutting your calorie intake well below your usual diet will add years to your life

More research is needed to test these health effects (Fladerer & Grollitsch, 2023)

R.CozzolinoF.RotilioG.et al (2003)
10.1001/archsurg.1985.01390320065013 50 KimH

Huang MT
