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[33] [26] [116] It is also contraindicated in individuals with advanced arteriosclerosis (hardening of the arteries), glaucoma (increased eye pressure), hyperthyroidism (excessive production of thyroid hormone), or moderate to severe hypertension

For the fatty metabolites, those that were upregulated in ITP patients included RvD 2 , eicosatetraenoic acids, Monolinolein, and phosphatidylcholine, all of which can be regulated by gut microbiota (39)

Nausea, abdominal discomfort, or gastroesophageal refluxall documented with tirzepatidecan interfere with sleep onset and maintenance

Visontay R, Rao RT, Mewton L