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In vivo assessment by 31P nuclear magnetic resonance spectroscopy

In clinical trials, NAC supplementation reduced markers of oxidative stress by 25% and improved glycemic control, with HbA1c levels decreasing by 1.2% after six months [63]

Hydrogen is an essential substance for nutrient transfer and acid-base reactions

Omission of the reducing step, which would prevent the release of glutathione residues and the generation of free sulfhydryl groups, resulted in absence of fluorescence ( Figure 2B ), supporting efficiency of the blocking step